Abstract Background Neuroblastoma (NB) patients with MYCN amplification or overexpression respond poorly to current therapies and exhibit extremely poor clinical outcomes. PI3K-mTOR signaling-driven deregulation of protein synthesis is very common in NB and various other cancers that promote MYCN stabilization. In addition. both the MYCN and mTOR signaling axes can directly regulate a... https://www.roneverhart.com/Roland-Blues-Cube-Stage-1x12-60-Watt-Combo-Amp-p24291/